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Hydrolysis:

The hydrolysis half-life value of the test chemical sodium naphthalene-1-sulfonate (CAS no. 130-14-3) can be expected to be in range 5 -6 years at pH 7 and 200-211 days at pH 8 and Hydrolysis rate constant in range 0.038 L/mol-sec – 0.04 L/mol-sec. Based on these half-life values, it is concluded that the test chemical sodium naphthalene-1-sulfonate is not hydrolysable.

Additional information

Hydrolysis:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical sodium naphthalene-1-sulfonate (CAS no. 130-14-3).The studies are as mentioned below.

The first experimental study was reviewed from authoritative database (HSDB, 2018) in this study the half-life and base catalyzed second order hydrolysis rate constant was determined using a structure estimation method of the test chemical. The second order hydrolysis rate constant of test chemical was determined to be 0.038 L/mol-sec with a corresponding half-life of 6 yrs and 211 days at pH 7 and 8, respectively. Based on the half-life values, it is concluded that test chemical is not hydrolysable.

Next experimental study was also reviewed from authoritative database mentioned above in this study the base catalyzed second order hydrolysis rate constant was determined using a structure estimation method. The second order hydrolysis rate constant is determined to be 4.0 × 10-2 L/mol-sec with a corresponding half lives of 5 years and 200 days at pH 7 and 8, respectively. Based on the half-life values, it is concluded that the test chemical is not hydrolysable.

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical sodium naphthalene-1-sulfonate (CAS no. 130-14-3) can be expected to be in range 5 -6 years at pH 7 and 200-211 days at pH 8 and Hydrolysis rate constant in range 0.038 L/mol-sec – 0.04 L/mol-sec. Based on these half-life values, it is concluded that the test chemical sodium naphthalene-1-sulfonate is not hydrolysable.