Registration Dossier

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

No water solubility value is reported

Key value for chemical safety assessment

Additional information

For solubility in water, OECD 105 was used as a starting point. To determine if the experiment should be outsourced to a contract lab using a qualified test method, preliminary experiments were conducted. Three lots were assessed with one replicate per lot (PF 264, PF 312, PF 321- storage condition minus 20 °C). The experiments were conducted using transaminase enzyme lyophilized powder in distilled water at 22 °C. With the initial aliquot of powder added to distilled water, there was an extremely small amount of insolubility from a component in the powder. As additional powder was added, the insoluble component increased – this continued until the mixture became a paste. Therefore, no water solubility value is reported.