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Physical & Chemical properties

Density

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Reference
Endpoint:
density, other
Remarks:
pour density; tap density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
GLP compliance:
no
Type of method:
other: pour & tapped density
Specific details on test material used for the study:
- Name of test material (as cited in study report): Piperazine citrate / tripiperazine dicitrate- Molecular formula: C12H30N6•Cl2H16O14 - Molecular weight: 642.76 g/mole - Substance type: Organic - Physical state: Solid
Key result
Type:
pour density
Density:
0.646 g/cm³
Temp.:
28.3 °C
Remarks on result:
other: Atmospheric pressure of 977.6 hPa
Key result
Type:
tap density
Density:
0.741 g/cm³
Temp.:
28.3 °C
Remarks on result:
other: Atmospheric pressure of 977.6 hPa

The pour density and tapped density of Tripiperazine dicitrate (CAS No. 144-29-6) was found to be 0.6458 gm/cm3at and 0.7407 gm/cm3at 28.3oC and  977.6 hPa.

Conclusions:
The density of test item Tripiperazine dicitrate (CAS No. 144-29-6) was determined following OECD Guideline 109 and according to the International Pharmacopoeia, fourth Edition, 2014 using glass cylinder. The pour density and tapped density of Tripiperazine dicitrate (CAS No. 144-29-6) was determined to be 0.6458 gm/cm3 at and 0.7407 gm/cm3 at 28.3°C and 977.6 hPa.
Executive summary:

The density of test item Tripiperazine dicitrate (CAS No. 144-29-6) was determined following OECD Guideline 109 and according to the International Pharmacopoeia, fourth Edition, 2014 using glass cylinder. The pour density and tapped density of Tripiperazine dicitrate (CAS No. 144-29-6) was determined to be 0.6458 gm/cm3 at and 0.7407 gm/cm3 at 28.3°C and 977.6 hPa.

Description of key information

The density of test item Tripiperazine dicitrate (CAS No. 144-29-6) was determined following OECD Guideline 109 and according to the International Pharmacopoeia, fourth Edition, 2014 using glass cylinder. The pour density and tapped density of Tripiperazine dicitrate (CAS No. 144-29-6) was determined to be 0.6458 gm/cm3 at and 0.7407 gm/cm3 at 28.3°C and 977.6 hPa.

Key value for chemical safety assessment

Relative density at 20C:
0.741

Additional information

The density of test item Tripiperazine dicitrate (CAS No. 144-29-6) was determined following OECD Guideline 109 and according to the International Pharmacopoeia, fourth Edition, 2014 using glass cylinder. The pour density and tapped density of Tripiperazine dicitrate (CAS No. 144-29-6) was determined to be 0.6458 gm/cm3 at and 0.7407 gm/cm3 at 28.3°C and 977.6 hPa.