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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010-02-18 to 2010-02-18
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Recent, well documented GLP and guideline study.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report Date:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Particle sizeopen allclose all
Percentile:
D50
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Percentile:
D10
Mean:
<= 8.61 µm
St. dev.:
0.026
Remarks on result:
other: RSD = 0.31 %
Percentile:
D50
Mean:
<= 76.9 µm
St. dev.:
1.36
Remarks on result:
other: RSD = 1.77 %
Percentile:
D90
Mean:
<= 195 µm
St. dev.:
4.2
Remarks on result:
other: RSD = 2.14 %

Any other information on results incl. tables

Dry dispersing system RODOS: Measurement starting with approximately 12 - 13 g powder for each test at a pressure of 1.5 bar. The measuring range of the optical system was set to lense R5 (0.5/4.5...875 µm).

Summary table

Run

X10

[µm]

X50

[µm]

X90

[µm]

1

8.63

77.76

191.93

2

8.62

77.67

193.96

3

8.58

75.36

199.97

Average

8.61

76.93

195.29

Standard Deviation

0.026

1.360

4.181

RSD [%]

0.31

1.77

2.14

 

The average particle size and standard deviation of the test item
1-Chloro-2,5-dimethoxy-4-nitrobenzene was

X10: ≤ 8.61 ± 0.026 pm
X
50: ≤ 76.9 ± 1.36 pm
X
90: ≤ 195 ± 4.2 pm


Applicant's summary and conclusion

Conclusions:
The Particle Size Distribution of the test item 1-Chloro-2,5-dimethoxy-4-nitrobenzene
was measured with Sympatec HELOS laser diffraction with dry dispersing system
RODOS.
The average and standard deviation of 3 determinations was:
X10: ≤ 8.61 ± 0.026 3m (RSD = 0.31 %)
X50: ≤ 76.9 ± 1.36 3m (RSD = 1.77 %)
X90: ≤ 195 ± 4.2 3m (RSD = 2.14 %)
Executive summary:

The Particle Size Distribution of the test item 1-Chloro-2,5-dimethoxy-4-nitrobenzene

was measured with Sympatec HELOS laser diffraction with dry dispersing system

RODOS.

The average and standard deviation of 3 determinations was:

X10: ≤ 8.61 ± 0.026 µm (RSD = 0.31 %)

X50: ≤ 76.9 ± 1.36 µm (RSD = 1.77 %)

X90: ≤ 195 ± 4.2 µm (RSD = 2.14 %)