Registration Dossier

Administrative data

Description of key information

LD50(oral) > 15000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
15 000 mg/kg bw
Quality of whole database:
Method equivalent or similar to guidelines internationally accepted.

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

No information about the "Acute oral toxicity" of the Target Substance is available. Nevertheless a study on a Similar Substance (Similar Substance 01) was used in order to fulfill regulatory requirements. Details about the structural similarity between the two substances are reported in section 13.

The substance was tested in 1977 by oral administration. The results of the test show a very high value of LD50. No death occurred during the test.

Justification for classification or non-classification

According to the CLP Regulation (EC) n. 1272/2008, acute toxicity means those adverse effects occurring following oral or dermal administration of a single dose of a substance or a mixture, or multiple doses given within 24 hours, or an inhalation exposure of 4 hours.

The substance is not classified according to table 3.1.1 of the CLP Regulation (EC) n. 1272/2008.