Registration Dossier
Registration Dossier
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EC number: 453-460-3 | CAS number: -
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil microorganisms
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
No effects of the test substance on terrestrial organisms are expected.
Key value for chemical safety assessment
Additional information
No studies on long-term terrestrial toxicity are available for this substance. Due to the high Koc a considerable adsorption to sediment and soil is indicated. However, the test item has been shown to be readily biodegradable. Therefore, no chronic exposure of terrestrial organisms is expected. Furthermore, the abstract of a terrestrial plant toxicity test (short-term, OECD 208, Kirch 1996) performed on the read-across substance Fatty acids, C14-18 and C16-18 unsatd., triesters with trimethylolpropane (CAS 68002-79-9) indicates no toxicity (NOEC = 300-1000 mg/kg soil dw, LOECs = 1000 mg/kg soil dw). In addition, Fatty acid esters are metabolised into fatty acids and alcohols. These components occur in sediment and soils naturally, are part of physiological pathways and can be used as energy source. The enzyme carboxylesterase is omnipresent in the environment, readily degrading this test substance. Thus, toxic effects caused by the metabolites of fatty acid esters are implausible.
In conclusion, due to a) the observed absence of toxicological effects on aquatic organisms (assumption that soil toxicity expressed in terms of the freely-dissolved substance concentration in the pore water is the same as aquatic toxicity, ECHA Guidance on Information Requirements Chapter R.10), b) the lack of chronic exposure and c) the, acknowledged metabolisation of fatty acid esters, toxic effects to terrestrial organisms can be excluded.
The justification for read-across is presented in Section 13 Assessment reports- Read-across justification.
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