Registration Dossier
Registration Dossier
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EC number: 200-891-8 | CAS number: 75-68-3
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The logKow value of 1-chloro-1,1-difluoroethane has been estimated by the model KowWin (v1.67) as follows: logKow = 2.05. In order to test the applicability of the model for the substance of interest, logKow of four other similar substances have been calculated (see the QPRF attached). The estimated logKow values are consitent to the experimental data reported in the same model, showing that the model is applicable to the concerned substance.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.05
- at the temperature of:
- 20 °C
Additional information
- The logKow value of 1-chloro-1,1-difluoroethane has been estimated by the model KowWin (v1.67) as follows: logKow = 2.05. In order to test the applicability of the model for the substance of interest, logKow of four other acids have been calculated (see the QPRF attached). The estimated logKow values are consitent to the experimental data reported in the same model, showing that the model is applicable to the concerned substance.
- The partition coefficient of the substance was also calculated according to Hansch and Leo method, and wass found to be 1.617.
- Information on the partition coefficient of the substance was taken from the original publication of Hansch and Leo (1979) which indicates a log Kow value 1.64.
No experimental value is available for1-chloro-1,1-difluoroethane nevertheless several estimations have been done for this key parameter.
Based on these these estimations, it can be considered that difluoromethane has a low potential for bioaccumulation and adsorption.
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