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Vapour pressure

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Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 18, 2016 - March 21, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes
Type of method:
spinning rotor
Key result
Temp.:
ca. 20 °C
Vapour pressure:
ca. 0.001 Pa
Remarks on result:
other:

The system offset pressure using a molecular weight of 368.551 g/mol was 5.3145 x 10-5Pa. The calculated mean measured vapor pressure of the test substance by the SRG method, using a molecular weight of 368.551 g/mol, was 1.49 x 10-3Pa at 20 ± 1°C. The measured vapor pressure ranged from a minimum of 1.21 x 10-3Pa to a maximum of 1.79 x 10-3Pa. Individual and mean measured vapor pressures and out-gassing rates for the test substance at 20 ± 1°C using a molecular weight of 368.551 g/mol are presented in the table below.

Table : Vapor Pressure Measurements and Out-Gassing Rates for the Test Substance

by the Spinning Rotor Gauge Method at 20 ± 1°C

 

 

Molecular Weight

(g/mol)

 

Measured

Vapor Pressure

(Pa)

Min/Max

Temperature

(°C)

Mean

Measured

Vapor Pressure

(Pa)

 

Standard

Deviation

(Pa)

 

1.21 x 10-3

 

 

 

368.551

1.46 x 10-3

19.8/20.0

1.49 x 10-3

2.91 x 10-4

 

1.79 x 10-3

 

 

 

 

 

 

 

Molecular Weight

(g/mol)

 

 

Measured

Out-gassing Rate

(Pa/s)

Min/Max

Temperature

(°C)

 

Mean

Measured

Out-gassing Rate

(Pa/s)

 

 

Standard

Deviation

(Pa/s)

 

7.88 x 10-6

 

 

 

368.551

7.50 x 10-6

19.8/20.0

7.39 x 10-6

5.48 x 10-7

 

6.80 x 10-6

 

 

 

 

Conclusions:
The mean vapor pressure for the test substance at 20 ± 1ºC was 1.49 x 10-3 ± 2.91 x 10-4 Pa (N = 3, CV = 20%) using the spinning rotor gauge method.
Executive summary:

The test was performedbased on procedures in the U.S. EPA Product Properties Test Guidelines, OPPTS 830.7950,Vapor Pressure(1) and OECD Guideline for Testing of Chemicals, 104,Vapour Pressure(2).

The mean vapor pressure for the test substance at 20 ± 1ºC was 1.49 x 10-3 ± 2.91 x 10-4 Pa (N = 3, CV = 20%) using the spinning rotor gauge method.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 June 2000 - 21 June 2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes
Type of method:
gas saturation method
Specific details on test material used for the study:
The neat test substance was stored at room temperature.
Key result
Test no.:
#1
Temp.:
50 °C
Vapour pressure:
< 0 Pa

See attached background document

Conclusions:
The test method's lower limit of detection was determined and used to calculate an upper limit vapor pressure value. Based on the 50°C run, the vapor pressure for the Substance was determined to be <4.30 x 10-6Pa for temperatures up to 50°C
Executive summary:

The vapor pressure of the Substance was determined employing the procedure outlined in the Organization for Economic Co-operation and Development (OECD) Test Guideline 104: "Vapor Pressure - Gas Saturation Method" and EU directive 67/548 EEC Method A.4 "Vapor Pressure". The vapor pressure of a test substance is a significant factor for predicting atmospheric concentrations.

A stream of nitrogen was passed over the test substance in such a way that the nitrogen became saturated with the test substance vapor which was then collected onto a suitable absorbent trap. Measurement of the amount of the test substance transported by a known amount of carrier gas was used to calculate the vapor pressure at a given temperature. Evaluation of the Substance at 40°C for 24 hours and 50°C for 48 hours showed no measurable vapor pressure. The test method's lower limit of detection was determined and used to calculate an upper limit vapor pressure value. Based on the 50°C run, the vapor pressure for the Substance was determined to be <4.30 x 10-6Pa for temperatures up to 50°C.

Description of key information

Two studies were performed on the registered substance.

 

The vapour pressure of the substance using the spinning rotor gauge was reported to be 0.00149 Pa at 20°C.

 

The vapour pressure of the substance using the gas saturation method was reported to be < 0.0000043 Pa at 50°C.

Key value for chemical safety assessment

Vapour pressure:
0.001 Pa
at the temperature of:
20 °C

Additional information

The test was performedbased on procedures in the U.S. EPA Product Properties Test Guidelines, OPPTS 830.7950,Vapor Pressure(1) and OECD Guideline for Testing of Chemicals, 104,Vapour Pressure(2).

The mean vapor pressure for the test substance at 20 ± 1ºC was 1.49 x 10-3 ± 2.91 x 10-4 Pa (N = 3, CV = 20%) using the spinning rotor gauge method.