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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18 Apr - 25 Jun 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP - guideline study
Principles of method if other than guideline:
The partition coefficient was estimated based on the individual ratio between the n-octanol soluble parts of the test item and the water soluble parts of the test item. To provide at least laboratory based results for the n-octanol soluble parts of the test item the soluble parts of a defined amount of the test item were determined as niobium by ICP-MS.
GLP compliance:
yes (incl. certificate)
Remarks:
LUBW Landesanstalt für Umwelt, Messungen und Naturschutz Baden-Württemberg, Karlsruhe, Germany
Type of method:
other: calculated from solubililty in water and n-octanol
Partition coefficient type:
octanol-water
Analytical method:
other: ICP-MS
Type:
Pow
Partition coefficient:
0
Temp.:
20 °C
pH:
0.43
Remarks on result:
other: The pH represents that of the water phase
Type:
log Pow
Partition coefficient:
-5.12
Temp.:
20 °C
pH:
0.43
Remarks on result:
other: The pH represents that of the water phase

Water solubility was determined at 20 °C and pH=0.43, the pH for the determination for solubility in n-octanol was not reported.

Time course of the measured soluble parts of Ammonium Niobium Oxalate at 20 °C in n-octanol:

Time / days

Sample

Weight sample in 300 mL n‑Octanol / g

Determined conc. of niobium / µg/L

Determined conc. of Ammonium Niobium Oxalate / µg/L

Mean determined conc. of Ammonium Niobium Oxalate ± RSD µg/L ± %

Mean soluble parts of Ammonium Niobium Oxalate in n‑octanol / µg/L

3

1

0.6460

306

1779

1602 ± 13.2

 

223

1297

2

0.6555

292

1698

281

1634

10

1

0.6460

476

2767

2426 ± 13.5

2490

453

2634

2

0.6555

383

2227

357

2076

12

1

0.6460

503

2924

2554 ± 18.2

514

2988

2

0.6555

373

2169

367

2134

POW= cn-octanol/cwater

With cn-octanol= soluble parts of Ammonium Niobium Oxalate in n-octanol / µg/L and cwater= soluble parts of test item in water / µg/L (325 g/L at 20 °C and pH=0.43)

POW= estimated partition coefficient

POW=7.662*10-6

The estimated log POW is approximately -5.12.

Description of key information

log Pow =-5.12 at 20 °C 

Key value for chemical safety assessment

Log Kow (Log Pow):
-5.12
at the temperature of:
20 °C

Additional information

The partition coefficient was estimated based on the individual ratio between the n-octanol soluble parts of the test item and the water soluble parts of the test item.