Registration Dossier
Registration Dossier
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EC number: 221-717-7 | CAS number: 3209-22-1
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo mammalian germ cell study: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1985
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available
Data source
Reference
- Reference Type:
- publication
- Title:
- Chemical mutagenesis testing in Drosophila. IV. Results of 45 coded compounds tested for the National Toxicology Program
- Author:
- Yoon, J.S. et al.
- Year:
- 1 985
- Bibliographic source:
- Environ Mutagen. 7(3):349-67.
Materials and methods
- Principles of method if other than guideline:
- Drosophila Sex-Linked Recessive Lethal Study
- GLP compliance:
- not specified
- Type of assay:
- Drosophila SLRL assay
Test material
- Reference substance name:
- 1,2-dichloro-3-nitrobenzene
- EC Number:
- 221-717-7
- EC Name:
- 1,2-dichloro-3-nitrobenzene
- Cas Number:
- 3209-22-1
- Molecular formula:
- C6H3Cl2NO2
- IUPAC Name:
- 1,2-dichloro-3-nitrobenzene
- Details on test material:
- - Name of test material (as cited in study report): 2,3-Dichloronitrobenzene
- Analytical purity: no data
Constituent 1
Test animals
- Species:
- Drosophila melanogaster
- Strain:
- other: not applicable
- Sex:
- male/female
Administration / exposure
- Route of administration:
- other: no data
- Duration of treatment / exposure:
- no data
- Frequency of treatment:
- no data
- Post exposure period:
- no data
Doses / concentrations
- Remarks:
- Doses / Concentrations:
no data
Basis:
no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Examinations
- Tissues and cell types examined:
- no data
Results and discussion
Test results
- Sex:
- not specified
- Genotoxicity:
- negative
- Toxicity:
- not specified
- Vehicle controls validity:
- not specified
- Negative controls validity:
- not specified
- Positive controls validity:
- not specified
Any other information on results incl. tables
No further information given.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results: negative
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