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Short-term toxicity to aquatic invertebrates

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Description of key information

No toxic effects to aquatic invertebrates up to the limit of water solubility (< 0.05 mg/L)

Key value for chemical safety assessment

Additional information

Three studies, investigating the short-term toxicity to aquatic invertebrates of Fatty acids, C16-18 even numbered and C18-unsatd. triesters with propylidynetrimethanol (CAS 57675-44-2) are available. In all three static studies with Daphnia magna according to OECD 202 the test solution was prepared with Water Accommodated Fraction (WAF). The key study (Häner, 2006) determined an EL0 (48 h) ≥ 100 mg/L and EL50 (48 h) > 100 mg/L and both supporting studies (Craig, 2005 and Källqvist, 1995) resulted in EL50 (48 h) > 1000 mg/L, whereas Källqvist observed an immobilisation of 18% at 1000 mg/L. Overall, low toxicities of Fatty acids, C16-18 even numbered and C18-unsatd. triesters with propylidynetrimethanol far in excess of natural occurring concentrations (water solubility < 0.05 mg/L) could be observed. Therefore, the substance is not harmful to aquatic invertebrates.

This is supported by several structurally similar category members. The acute toxicity of Fatty acids, C16-18 and C18-unsatd., triesters with trimethylolpropane (CAS 68002-78-8) to aquatic invertebrates was tested in a study following OECD guideline 202 (Bouillon, 2012). Daphnia magna were exposed to the test substance in a static test system for 48 hours. The test was performed as a limit test with a loading ratio of 0.106 g (substance)/1000 g (test medium). An EL50 >106 mg/L based on the nominal concentration of the water accommodated fraction of the test substance was reported. Therefore acute toxic effects on aquatic invertebrates are not expected within the range of the water solubility of the substance (<0.05 mg/L; Frischmann, 2012).

Based on these results both from Fatty acids, C16-18 even numbered and C18-unsatd. triesters with propylidynetrimethanol  and from structurally related read-across substances (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which are characterized by a similar ecotoxicological profile, it can be concluded that Fatty acids, C16-18 even numbered and C18-unsatd. triesters with propylidynetrimethanol will not exhibit short-term toxic effects to aquatic invertebrates up to the limit of water solubility.