Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 436-710-6 | CAS number: 756-13-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Exposure of Pseudokirchneriella subcapitata to CAS# 756-13-8 resulted in 72 and 96 hour EC50s (based on average specific growth rate) that were greater than the nominal loading rate.
CAS# 756-13-8 was added to the stock solutions at 150 mg/L, which is in excess of water solubility. The dissolved material hydrolyzed completely with a half life of less than 2.5 minutes to water-soluble perfluoropropionic acid (PFPA) and a volatile hydrofluorocarbon (heptafluoropropane). PFPA was quantified at 6.78 mg/L in the stock solution. This concentration of perfluoropropionic acid caused a decrease in average specific growth rate and number of cells per milliliter, but did not cause any size differences, unusual cell shapes, colors, flocculations, adherence to test containers, or aggregations. The 72-hour and 96-hour EC50s based on average specific growth rate were >6.78 mg/L as PFPA. The 96-hour NOEC based on average specific growth rate was 3.47 mg/L as PFPA.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 6.78 mg/L
- EC10 or NOEC for freshwater algae:
- 3.47 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
