Registration Dossier
Registration Dossier
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EC number: 231-493-2 | CAS number: 7585-39-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of the present test .beta.-Cyclodextrin induced no lethal effects in carp at or below 4500 mg/l, the LC50 was 7561 mg/l.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 7 561 mg/L
Additional information
A 96-Hour Acute Toxicity study in Carp was performed with .beta.-Cyclodextrin. The study procedures were based on the OECD guideline No. 203, Adopted 17 July, 1992. Initially, a limit test was performed with carp exposed to 100 mg/l in a
static system. No visible effects occurred during the 96-hour test period. Hence, the 96h-LC50 for carp exposed to .beta.-Cyclodextrin was >100 mg/l. An additional limit test was performed with seven carp exposed to a concentration of 10,000 mg/l. Six out of seven carp exposed died within 24 hours of exposure. Hence, a second final test was performed with seven carp exposed to concentrations ranging from 1000 to 10,000 mg/l in a static system to determine the LC50. The 96-hour LC50 was already reached after 24 hours of exposure. The LC50 was 7561 mg/l, the NOEC was 4500 mg/l.
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