Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: (Q)SAR
Title:
Estimation Programs Interface Suite™ for Microsoft® Windows, v 4.11 (EPIWEB 4.11)
Author:
United States Environmental Protection Agency, Washington, DC, USA.
Year:
2012
Bibliographic source:
ECOSAR (v1.11)

Materials and methods

Test guideline
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test organisms

Test organisms (species):
other aquatic crustacea: Daphnid

Study design

Test type:
other: (Q)SAR
Water media type:
freshwater

Results and discussion

Effect concentrations
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
3.938 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 5.0 (Daphnid LC50)
Conclusions:
Estimated LC50 (48 h) : 3.9 mg/L
Intermediate substance is estimated to be toxic to aquatic invertebrates (acute toxicity).