Registration Dossier
Registration Dossier
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EC number: 205-429-9 | CAS number: 140-73-8
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 01, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM D 1766-90
- GLP compliance:
- no
- Type of method:
- flask method
- Water solubility:
- ca. 44 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 25 °C
- pH:
- ca. 7.88
- Details on results:
- The solubility of the test substance in water at 25 ºC, expressed as g/l, was calculated by applying the following formula:
S (g/l) = (B – A)*1000/25 = C/0.025
where:
A: tare of the volumetric flask
B: lord weight of the volumetric flask
C: mass of solute initially contained in 25 cm3 of solution - Conclusions:
- The water solubility of the test substance is 44 mg/l at 25°C.
- Executive summary:
Method
The substance has been tested for water solubility according to the flask method as reported in the ASTM D 1766-90 standards.
Results
The water solubility of the substance is 44 mg/l at 25 °C and pH ca 7.88.
Reference
The precision of the method requires that the two net masses of solute, obtained from the test performed in duplicate, should not differ more than 10 % of each other. If agreement within 10 % is obtained, the average mass of solute should be used to determine the solubility of the product in water at 25 °C.
The difference between the net masses of solute, obtained from the test performed in duplicate, is equal to 0.00009 g, which value represents about 8.5 % of the measured masses. The tests showed a precision lower than the limit imposed by the method and can be considered as valid.
The value of the solubility of the test substance in water at 25 °C is given by the average net mass of the solute, which resulted to be equal to 0.001105 g.
Description of key information
Water solubility = 44 mg/l at 25°C
Key value for chemical safety assessment
- Water solubility:
- 44 mg/L
- at the temperature of:
- 25 °C
Additional information
The substance has been tested for water solubility according to the flask method as reported in the ASTM D 1766-90 standards.
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