Registration Dossier
Registration Dossier
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EC number: 635-476-4 | CAS number: 88349-88-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No studies of toxicity to microorganisms have been performed with cloquintocet acid, however a reliable study of the inhibition of respiration by activated sludge is available for cloquintocet-mexyl, a close structural analog of cloquintocet acid, and has been used for read-across purposes. Given the close similarity between the source substance (cloquintocet-mexyl) and the target compound (cloquintocet acid), and the fact that the target is also an initial hydrolysis degradate of the source, the inhibition endpoints obtained for cloquintocet-mexyl are considered to provide an adequately reliable estimate of the microbial toxicity of cloquintocet acid.
The 3 -hour EC50 based on inhibition of respiration of activated sludge micro-organisms exceeded 1000 mg cloquintocet-mexyl/L. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/L (the highest concentration tested). The same endpoints are considered to apply equally to cloquintocet acid.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
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