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EC number: 220-977-9 | CAS number: 2956-12-9
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial arthropods: long-term
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because direct and indirect exposure of the soil compartment is unlikely
- other:
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- other: published data
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Carbon disulphide (CAS number 75–15–0) is both reagents used in the manufacture of S-allyl O-pentyl dithiocarbonate. Therefore, Carbon disulphide (CAS number 75–15–0) need to be considered in the assessment of S-allyl O-pentyl dithiocarbonate.
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
- Application method:
- spray
- Analytical monitoring:
- not specified
- Vehicle:
- no
- Test organisms (species):
- Apis mellifera
- Animal group:
- Hymenoptera (honeybees)
- Study type:
- field study
- Limit test:
- no
- Total exposure duration:
- 4 h
- Reference substance (positive control):
- no
- Duration:
- 1 h
- Dose descriptor:
- other: NOEL
- Effect conc.:
- 75 other: ml/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: Chemical avoidance
- Duration:
- 4 h
- Dose descriptor:
- other: NOEL
- Effect conc.:
- 75 other: ml/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- other: Chemical avoidance
- Duration:
- 1 h
- Dose descriptor:
- other: NOEL
- Effect conc.:
- 201.3 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- S-allyl O-pentyl dithiocarbonate
- Basis for effect:
- other: Chemical avoidance
- Remarks on result:
- other: On a molecular weight scaled basis, the NOEL would be 201.3 mg/kg soil. (75 x 204.35) /76.13 =201.3 mg/kg soil
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Substance appears to have no significant adverse effect on bees
- Endpoint:
- toxicity to terrestrial arthropods: short-term
- Type of information:
- other: published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Carbon disulphide (CAS number 75–15–0) is both reagents used in the manufacture of S-allyl O-pentyl dithiocarbonate. Therefore, Carbon disulphide (CAS number 75–15–0) need to be considered in the assessment of S-allyl O-pentyl dithiocarbonate.
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The egg(s) (age: 2 d and organism characteristics of: NR) were exposed for a duration of 7 hour(s) to a(n) 1 dosed x time(s) per study period application of Carbon disulfide
- GLP compliance:
- not specified
- Application method:
- other: fumigation
- Analytical monitoring:
- not specified
- Vehicle:
- no
- Test organisms (species):
- other: Sitophilus oryzae (Rice Weevil)
- Animal group:
- Coleoptera (soil-dwelling rove beetle)
- Details on test organisms:
- Egg(s) of Sitophilus oryzae (Rice Weevil) (age: 2 d )
Kingdom: Animalia
Phylum: Arthropoda
Class: Insecta
Order: Coleoptera
Family: Curculionidae
Genus: Sitophilus
Species: S. oryzae
2 mm long with a long snout. - Study type:
- laboratory study
- Limit test:
- no
- Total exposure duration:
- 7 h
- Nominal and measured concentrations:
- DOSES-50 to 175 mg/L
- Reference substance (positive control):
- no
- Duration:
- 7 h
- Dose descriptor:
- LC50
- Effect conc.:
- 75 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality
- Duration:
- 7 h
- Dose descriptor:
- LC50
- Effect conc.:
- 199.4 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- S-allyl O-pentyl dithiocarbonate
- Basis for effect:
- mortality
- Remarks on result:
- other: On a molecular weight scaled basis, the LC50 would be 201.32 mg/kg soil. (75 x 204.35) /76.13 =201.32 mg/kg soil
- Details on results:
- The LC50 for morality effects in Egg(s) of Sitophilus oryzae (Rice Weevil) by CS2 is 75mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 201.32 mg/kg soil. (75 x 204.35) /76.13 =201.32 mg/kg soil - Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC50 for morality effects in Egg(s) of Sitophilus oryzae (Rice Weevil) by CS2 is 75mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 201.32 mg/kg soil. (75 x 204.35) /76.13 =201.32 mg/kg soil - Endpoint:
- toxicity to terrestrial arthropods: long-term
- Type of information:
- other: published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Carbon disulphide (CAS number 75–15–0) is both reagents used in the manufacture of S-allyl O-pentyl dithiocarbonate. Therefore, Carbon disulphide (CAS number 75–15–0) need to be considered in the assessment of S-allyl O-pentyl dithiocarbonate.
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Trogoderma granarium (Skin Beetle) age: 2-3 d were exposed for a duration of 7 day(s) to a(n) 24 hour application of Carbon disulfide
- GLP compliance:
- not specified
- Application method:
- other: fumigation
- Analytical monitoring:
- not specified
- Vehicle:
- no
- Test organisms (species):
- other: Trogoderma granarium (Skin Beetle)
- Animal group:
- Coleoptera (soil-dwelling rove beetle)
- Details on test organisms:
- Trogoderma granarium (Skin Beetle). The pupa(e) (age: 2-3 d
- Study type:
- laboratory study
- Limit test:
- no
- Total exposure duration:
- 7 d
- Reference substance (positive control):
- no
- Duration:
- 7 d
- Dose descriptor:
- LC50
- Effect conc.:
- 6.8 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality
- Duration:
- 7 d
- Dose descriptor:
- LC50
- Effect conc.:
- 18.08 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Remarks:
- S-allyl O-pentyl dithiocarbonate
- Basis for effect:
- mortality
- Remarks on result:
- other: On a molecular weight scaled basis, the LC50 would be 18.25 mg/kg soil dw. (6.8 x 204.35) /76.13 =18.25 mg/kg soil dw
- Details on results:
- The LC50 for morality effects inTrogoderma granarium (Skin Beetle) by CS2 is 6.8 mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 18.25 mg/kg soil dw. (6.8 x 204.35) /76.13 =18.25 mg/kg soil dw - Validity criteria fulfilled:
- not specified
- Conclusions:
- The LC50 for morality effects inTrogoderma granarium (Skin Beetle) by CS2 is 6.8 mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 18.25 mg/kg soil dw. (6.8 x 204.35) /76.13 =18.25 mg/kg soil dw
Referenceopen allclose all
A study of NC-NC Not Coded duration using no substrate media was conducted in a FIELDN site location with Not Coded obtained Apis mellifera (Honey Bee). The organism(s) (age: NR NR and organism characteristics of: NR) were exposed for a duration of 1 hour(s) to a(n) 1 dosed x time(s) per study periodapplication of Carbon disulfide (CAS # 75150) in NR or a(n) NR positive control through a(n) hand spray exposure route. The reported chemical concentrations are the result of unmeasured analysis of chemical solutions and are based on the NR ion. (Reference 81711, Mayer,D.F., J.D. Lunden, G. Kovacs, and E.R. Miliczky, 2001, Test Number 571193)
A study of NC-NC Not Coded duration using no substrate media was conducted in a LAB site location with Not Coded obtained Sitophilus oryzae (Rice Weevil). The egg(s) (age: 2 d and organism characteristics of: NR) were exposed for a duration of 7 hour(s) to a(n) 1 dosed x time(s) per study period application of Carbon disulfide (CAS # 75150) in NR or a(n) NR positive control through a(n) fumigation exposure route. The reported chemical concentrations are the result of unmeasured analysis of chemical solutions and are based on the NR ion. (Reference 98146, Mostafa,S.A.S., A.H. Kamel, A.K.M. El-Nahal, and F.M. El-Borollosy, 1972, Test Number 445269).
A study of NC-NC Not Coded duration using no substrate media was conducted in a LAB site location with Not Coded obtained Trogoderma granarium (Skin Beetle). The pupa(e) (age: 2-3 d and organism characteristics of: NR) were exposed for a duration of 7 day(s) to a(n) 24 hour application of Carbon disulfide (CAS # 75150) in NR or a(n) NR positive control through a(n) fumigation exposure route. The reported chemical concentrations are the result of unmeasured analysis of chemical solutions and are based on the NR ion. (Reference 98144, Punj,G.K., and A.N. Verma, 1970, Test Number 445233).
Description of key information
The LC50 for morality effects in Egg(s) of Sitophilus oryzae (Rice Weevil) by CS2 is 75 mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 201.32 mg/kg soil. (75 x 204.35) /76.13 =201.32 mg/kg soil
The LC50 for morality effects inTrogoderma granarium (Skin Beetle) by CS2 is 6.8 mg/kg soil dw.
On a molecular weight scaled basis, the LC50 would be 18.25 mg/kg soil dw. (6.8 x 204.35) /76.13 =18.25 mg/kg soil dw
(NOEC=3.6 mg/kg soil dw).
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil dwelling arthropods:
- 201.32 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil dwelling arthropods:
- 3.6 mg/kg soil dw
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
