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Water solubility

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Description of key information

>=548.3 mg/L (active ingredient)

Key value for chemical safety assessment

Additional information

The water solubility of the active ingredient of Mexoryl SBO was estimated by a model calculation using the partition coefficient of the test item. Its water solubility at 25 °C was estimated to be 548.3 mg/L for the active ingredient. The present formulation of Mexoryl SBO is based on water. The content of the active ingredient is higher than the estimated water solubility as stated above. There might be different reasons for this finding: the water solubility was calculated based on the partition coefficient and therefore on the neutral form of the active ingredient. However, the active ingredient mainly exists in its sodium form, and therefore the water solubility is expected to be higher. In addition the solubilizer dipropylene glycol is used in the formulation and can increase the solubility of the neutral form. As the formulation of Mexoryl SBO based on water, it is therefore miscible with water at any ratio.