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Administrative data

Description of key information

skin irritation: substance was applied into the inside of the ear of a rabbit. result:  not irritating
eye irritation: substance was applied into the conjunctival sac of rabbits: result: slightly irritating

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

Skin irritation/corrosion: No skin reactions (erythema and edema score = 0) were seen after an application of the test substance for 8 hours, therefore the test substance is regarded as not irritating

Eye irritation: No effects on cornea and iris were seen in both animals after the application of the test substance.

During the post-observation time the erythema and edema scores of both amimals were below 2.

Therefore a classification is not justified.

Effects on eye irritation: slightly irritating

Justification for classification or non-classification

Due to the results of the skin irritation/corrosion study and the eye irritation study a classification is not justified