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Environmental fate & pathways

Hydrolysis

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Description of key information

Hydrolysis at the oxime moiety may take place. However, abiotic degradation is not a relevant degradation pathway of the substance in the environment.

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Additional information

One study investigating the hydrolytic stability of 5-(C11-C12 alkyl, branched)-2-hydroxy-benzaldehyde (CAS 1233873-37-4) under environmental conditions is available (Frischmann 2010). The study was performed according to test method L142C/518-532 C.7. Because of the relatively low water solubility and the complex structure of the substance, a pretest was performed with the aim to improve the solubility of the test substance in water. A stock solution of the test substance was prepared in acetone (50 mg test substance in 2 mL). When adding the stock solution to 1000 mL of water, a white precipitate was produced immediately. This indicates that based on the low water solubility and complex structural composition (UVCB) a hydrolysis test is not feasible with this substance.

Based on literature about hydrolysis of oximes and observations in the algae test it can, however, be assumed that hydrolysis at the oxime moiety of the test substance can take place. For instance, Egberink and van Heerden (1980) show pH and temperature depending hydrolysis of cyclohexanone oxime to hydroxylamine and cyclohexanone under environmental conditions.

Hydrolysis of 5-(C11-C12 alkyl, branched)-2-hydroxy-benzaldehyde would lead to the formation of the respective aldehyde and hydroxylamine. Further hydrolysis is due to structural reasons not possible. Thus, abiotic degradation is not a relevant degradation pathway of the substance in the environment. Further hydrolysis tests are ongoing to specifiy these assumptions. The results will be entered in the dossier as soon as they are available.