Registration Dossier

Administrative data

First-aid measures

Description of first aid measures:
General advice: Take the victim out of the contaminated area. Remove contaminated clothing immediately and dispose of safely.
If inhaled: Move to fresh air. Make the victim blow his nose. Seek medical advice.
In case of skin contact: Rinse immediately with plenty of water for at least 15 minutes. Seek medical advice.
In case of eye contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Seek medical advice immediately.
If swallowed: Do not induce vomiting. Make the victim rinse his mouth with water. Seek medical advice immediately.

Most important symptoms and effects, both acute and delayed
Symptoms: Dizziness. Drowsiness. Irritability Convulsions Tremors. Hypotensive effect. Bradycardia. Irritations.

Fire-fighting measures

Extinguishing media:
Suitable extinguishing media: All means (e.g. water, carbon dioxide, dry chemical extinguisher).
Extinguishing media that must not be used for safety reasons: Strong water jet.

Special hazards arising from the substance or mixture:
In case of fire, the product may emit toxic and/or irritating fumes. Supposed thermal decomposition/oxidation: Carbon monoxide and carbon dioxide Nitrogen oxides (NOx)

Advice for firefighters:
Special protective equipment for firefighting: Use self-contained breathing apparatus. Wear full protective suit.
Further information: Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Avoid rejection of extinguishing water in the environment.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:
Particle full face respirator or powered air purifying respirator. Suitable gloves. Dedicated work clothes.

Environmental precautions:
Avoid any spreading of product.

Methods and materials for containment and cleaning up:
General advice: Sweep and shovel the solid product in a container adapted for its recovery or destroying (avoiding dust formation). Close and label rigorously.
Cleaning of contaminated zone: After taking up the product, rinse the polluted area with water.
Elimination of recovered materials: Deliver to Environmental service of the factory or to any specialized and approved disposal service.

Additional advice:
Evacuation of area and intervention of special services recommended.

Handling and storage

Precautions for safe handling:
Advice on safe handling (industrial scale): Local ventilation and emission point dust extraction. Enclosed transfer recommended. Take precautionary measures against electrostatic loading. Earth vessels and equipment well.
Advice on safe handling (laboratory scale): Handling in a hood.

Conditions for safe storage, including any incompatibilities:
Requirements for storage rooms and vessels: Keep containers tightly closed in a cool, well-ventilated place. Keep locked-up.
Advice on common storage: Keep away from chemicals as it is a pharmaceutical substance
Further information on storage conditions: Keep in a well closed container, away from moisture and light.
Storage temperature: Keep at ambient temperature.
Packaging material advised: Glass, polyethylene, polypropylene.Light-resistant container.
Packaging material not advised: Many metals.
Sensitivity: No particular observation.

Transport information

Land transport (ADR/RID)

UN number:
1544
Proper shipping name and description:
ALKALOID SALTS, SOLID, N.O.S. (Thebaine tartrate)
Class:
6.1
Packaging group:
III
Labels:
60
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Marine transport (IMDG)

UN number:
1544
Proper shipping name and description:
ALKALOID SALTS, SOLID, N.O.S. (Thebaine tartrate)
Class:
6.1
Packaging group:
III
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
1544
Proper shipping name and description:
ALKALOID SALTS, SOLID, N.O.S. (Thebaine tartrate)
Class:
6.1
Packaging group:
III
Remarksopen allclose all
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Exposure controls / personal protection

Concentration limits in air:
OEL-8h (Sanofi): 45 μg/m3

Exposure controls:
Personal protective equipment
(IMPORTANT: to be adapted following the workplace risk assessment.)
Special recommendations: Pregnant women, seek medical advice before handling. Specific dermal hazard: avoid any contact with skin. Warning drivers of machines on risks of drowsiness.

Workshop
Respiratory protection: Particle full face mask or powered-air purifying respirator.
Hand protection: Suitable gloves. Glove material : Nitrile rubber Layer thickness : 0,11 mm Break through time: > 480 min
Eye protection: See respiratory protection.
Body Protection: Dedicated working clothes recommended.
Hygiene measures: Wash hands.

Laboratory
Respiratory protection: Handling in a hood.
Hand protection: Suitable gloves.
Eye protection: Safety glasses.
Body Protection: Working clothes.
Hygiene measures: Wash hands.

Stability and reactivity

Safety remarks: Dust may be explosive (no data available).

Incompatible materials: Strong acids and oxidizing agents
Hazardous decomposition products: Supposed thermal decomposition/oxidation: Carbon monoxide and carbon dioxide Nitrogen oxides (NOx)

Disposal considerations

Product: Deliver to the Environmental service of the factory or to any specialized and approved disposal service. Classified as NARCOTIC drug. Alert the competent authority.
Uncleaned packaging: Deliver to the Environmental service of the factory or to any specialized and approved disposal service.