Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Adequacy of study:
other information

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
2013

Materials and methods

Study type:
study with volunteers

Method

Route of exposure:
dermal
Reason of exposure:
intentional

Results and discussion

Any other information on results incl. tables

Results demonstrated increases in MBP in serum and urine within a few hours of application. An average of 1.82 % (range 0.11–5.94 %) of the applied DBP dose was recovered in urine as MBP during the treatment week.

Applicant's summary and conclusion

Executive summary:

The study (Janjua et al. 2007 ND, 2008 ND) suggests that DBP absorption via the dermal route in humans under conditions of usual cosmetic application is low.