Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The mutagenicity studies in bacteria and in mammalian cells in vitro as well as the chromosome aberration study performed in vitro were all negative. The substance is therefore considered to be non-mutagenic and non-clastogenic.

Justification for selection of genetic toxicity endpoint
Three standard mutagenicity / clastogenicity studies in vitro

Short description of key information:
Evaluation of the mutagenic activity in the bacterial reverse mutation assay and in an in vitro mammalian cell gene mutation test as well as in an in vitro chromosome aberration test in cultured peripheral human lymphocytes.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Based on the above stated assessment of the genotoxic potential (Ames test negative, in vitro mammalian cell gene mutation test negative, in vitro Chromosomme aberration mammalian cells negative) the substance is deemed non-genotoxic and accordingly does not need to be classified according to Council Directive 2001/59/EC (28th ATP of Directive 67/548/EEC) or according CLP (Regulation (EC) No 1272/2008 Of The European Parliament And Of The Council) as implementation of UN-GHS in the EU.