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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1977

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
not specified
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
3-methyl-2-pent-2-enylcyclopent-2-enone
EC Number:
207-668-4
EC Name:
3-methyl-2-pent-2-enylcyclopent-2-enone
Cas Number:
488-10-8
Molecular formula:
C11H16O
IUPAC Name:
3-methyl-2-pent-2-enylcyclopent-2-enone
impurity 1
Chemical structure
Reference substance name:
(E)-3-methyl-2-(pent-2-enyl)cyclopent-2-en-1-one
EC Number:
228-410-7
EC Name:
(E)-3-methyl-2-(pent-2-enyl)cyclopent-2-en-1-one
Cas Number:
6261-18-3
Molecular formula:
C11H16O
IUPAC Name:
3-methyl-2-pent-2-en-1-ylcyclopent-2-en-1-one
Test material form:
liquid

Test animals

Species:
rabbit

Administration / exposure

Type of coverage:
not specified
Vehicle:
unchanged (no vehicle)
Doses:
5000 mg/ kg bw
No. of animals per sex per dose:
10
Control animals:
not specified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.
Mortality:
none
Clinical signs:
other: Diarrhea in 1 animal on day 14.
Gross pathology:
Necropsy findings routine

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
LD50 >5000 mg/kg bw.