Registration Dossier
Registration Dossier
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EC number: 207-668-4 | CAS number: 488-10-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- June 1971
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: 2 page summary available, but study not done to guideline and not GLP.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1971
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The limits of confidence were determined by the method of Litchfield and Wilcoxon.
- GLP compliance:
- not specified
- Test type:
- fixed dose procedure
- Limit test:
- no
Test material
- Reference substance name:
- 3-methyl-2-pent-2-enylcyclopent-2-enone
- EC Number:
- 207-668-4
- EC Name:
- 3-methyl-2-pent-2-enylcyclopent-2-enone
- Cas Number:
- 488-10-8
- Molecular formula:
- C11H16O
- IUPAC Name:
- 3-methyl-2-pent-2-enylcyclopent-2-enone
- Reference substance name:
- (E)-3-methyl-2-(pent-2-enyl)cyclopent-2-en-1-one
- EC Number:
- 228-410-7
- EC Name:
- (E)-3-methyl-2-(pent-2-enyl)cyclopent-2-en-1-one
- Cas Number:
- 6261-18-3
- Molecular formula:
- C11H16O
- IUPAC Name:
- 3-methyl-2-pent-2-en-1-ylcyclopent-2-en-1-one
- Test material form:
- liquid
Constituent 1
impurity 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 3500 mg/kg, 4000 mg/kg, 4500 mg/kg
- No. of animals per sex per dose:
- 3500 mg/kg = 9
4000 mg/kg = 9
4500 mg/kg = 10 - Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 4 300 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- sligthly toxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Executive summary:
LD50 = 4300 mg/kg
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