4-methoxyphenylacetic acid

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-01-18 – 2017-01-18

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental result performed using standard methods of guideline.

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Principles of method if other than guideline:

The melting point determination of Test item 4-methoxyphenylacetic acid (CAS No. 104-01-8) was done as per the test guideline OECD 102.

GLP compliance:

no

Type of method:

other: Capillary/metal block.

Specific details on test material used for the study:

- Name of the test material: 4-methoxyphenyl)acetic acid
- Molecular formula: C9H10O3
- Molecular weight: 166.175 g/mol
- Substance type: Organic
- Purity: No data

Key result

Melting / freezing pt.:

>= 85.2 - <= 90.2 °C

Atm. press.:

977.2 hPa

Decomposition:

no

Sublimation:

no

Conclusions:

The melting point determination of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined to be in the range of 85.2 °C-90.2°C at 977.2hPa.

Executive summary:

The melting point determination of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined  to be in the range of 85.2 °C-90.2°C at 977.2hPa.

Description of key information

The melting point determination of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined  to be in the range of 85.2 °C-90.2°C at 977.2hPa.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

85.2 °C

Additional information

The melting point determination of 4-methoxyphenylacetic acid (CAS No. 104-01-8) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined  to be in the range of 85.2 °C-90.2°C at 977.2hPa.

Other supporting studies from various reliable sources such as authoritative database and handbooks,the melting point of chemical 4-methoxyphenyl)acetic acid was reported to be in the range of 84 degree C to 88 degree C.

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting point temperature in the range of 85.2 °C-90.2°C at 977.2 hPa, thus considered as key study for the chemical safety assessment.