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EC number: 606-722-8 | CAS number: 211915-06-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 004
- Report date:
- 2004
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- ß-Alanin,N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ethylester
- EC Number:
- 606-722-8
- Cas Number:
- 211915-06-9
- Molecular formula:
- C34 H41 N7 O5
- IUPAC Name:
- ß-Alanin,N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-ethylester
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, adapted
- Duration of test (contact time):
- 29 d
Initial test substance concentration
- Initial conc.:
- 30.7 mg/L
- Based on:
- test mat.
- Remarks:
- 20 mg organic carbon/L (corresponding to 30.7 mg test item/L)
Reference substance
- Reference substance:
- aniline
- Remarks:
- Penylamine, C6H5NH2, CAS-Nr. 62-53-3
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 1.8
- Sampling time:
- 7 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 4.7
- Sampling time:
- 14 d
- Parameter:
- % degradation (test mat. analysis)
- Value:
- ca. 13.5
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- - The test item can be considered as "not readily biodegradable"
- The degree of biodegradation reached 14% after 28 days.
- The 10d-window was not detectable.
- The abiotic degradation reached 13%.
Validity:
- The IC content of the flasks at the beginning of the test was <5% of the TC (criterion: ≤ 5% of TC).
- The degree of CO2 emitted by the controls was 32.3 mg/L (criterion: ≤ 40 mg/L).
- The difference within replicates on day 28 was < 1% (criterion: ≤ 20%).
-The reference compound reached the pass level of 60% on day 7 (criterion: ≤ 14 days).
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