Registration Dossier

Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: CIPAC Method MT 59 and MT 170
GLP compliance:
no
Type of method:
sedimentation (gravitational settling)

Test material

Constituent 1
Chemical structure
Reference substance name:
9β,11β-epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
EC Number:
213-563-4
EC Name:
9β,11β-epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
Cas Number:
981-34-0
Molecular formula:
C22H28O5
IUPAC Name:
17,21-dihydroxy-16-methyl-9,11-epoxypregna-1,4-diene-3,20-dione
Test material form:
solid: particulate/powder

Results and discussion

Particle size distribution at different passagesopen allclose all
No.:
#1
Size:
0.71 mm
Distribution:
11.89 %
No.:
#2
Size:
0.5 mm
Distribution:
24.98 %
No.:
#3
Size:
0.355 mm
Distribution:
37.7 %
No.:
#4
Size:
0.25 mm
Distribution:
62.62 %
No.:
#5
Size:
0.125 mm
Distribution:
98 %
No.:
#5
Size:
0.075 mm
Distribution:
99.2 %
No.:
#7
Size:
< 0.045 mm
Distribution:
99.96 %

Applicant's summary and conclusion

Conclusions:
From the obtained experimental data according to CIPAC method MT 59 and MT 170, it can
be concluded that, after 5 minutes of shaking, the particle size distribution of BETAMETHYLEPOXY
is: 11.89% of the sample presents a particle size higher than 0.710 mm
(710 μm), 24.98% of the sample presents a particle size higher than 0.500 mm (500 μm),
37.70% of the sample presents a particle size higher than 0.355 mm (355 μm), 62.62% of the
sample presents a particle size higher than 0.250 mm (250 μm), 98.00% of the sample
presents a particle size higher than 0.125 mm (125 μm), 99.20% of the sample presents a
particle size higher than 0.075 mm (75 μm) and 0.76% of the sample was found under 0.045
mm (45 μm).