Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic / sediment:

The estimated bio concentration factor (BCF) for tetrabutylammonium hydrogen sulphate is 70.79 L/kg whole body w.w which does not exceed the bio concentration threshold of 2000. Thus it is concluded that tetrabutylammonium hydrogen sulphate is not expected to bioaccumulate in the food chain.

Additional information

Bioaccumulation: aquatic / sediment:

For bioaccumulation in aquatic environment, 3 studies for the test chemical Tetrabutylammonium hydrogen sulphate (Cas no. 32503-27-8) were reviewed as follows:

From the EPI suite Program (2017); using BCFBAF (v3.01) model the Bioaccumulation factor (BCF) was predicted to be 70.79 L/kg wet-wt at 25 deg.C for target tetrabutylammonium hydrogen sulphate which does not exceed the bio concentration threshold of 2000. Thus it is concluded that tetrabutylammonium hydrogen sulphate is not expected to bioaccumulate in the food chain.

Another prediction database PBT profiler; 2017 indicated the Bioaccumulation factor (BCF) was predicted to be 71 L/kg wet-wt at 25 deg.C for target chemical tetrabutylammonium hydrogen sulphate.

 

In addition, a study from Japan chemicals collborative knowledge database (J-check); 2017 for the read across chemical Tetra-n-propylammonium bromide (Cas no. 1941-30-6) indicate that according to guideline OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish), the BCF value for Tetra-n-propylammonium bromide (Cas no. 1941-30-6) was determined to be <= 0.3 L/kg at dose concentration 2 mg/L and <= 2.8 L/kg at dose concentration 0.2 mg/L on test organism Cyprinus carpio during 6 weeks period. Thus based on the BCF value it is concluded that the test substance Tetra-n-propylammonium bromide is non bioaccumulative in nature.

 

Experimental study data of read across chemical supports the predicted result of the target chemical which indicate the Bioaccumulation value (BCF) is in the range <= 0.3 -71 for target chemical Tetrabutylammonium hydrogen sulphate.Thus based on available BCF range, we can conclude that the test substance Tetrabutylammonium hydrogen sulphate (Cas no. 32503-27-8) is non bioaccumulative in aquatic environment.