Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: screening tests
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report Date:
2015

Materials and methods

Principles of method if other than guideline:
The ready biodegradability was estimated by using BIOWIN, Toxtree and Vega predictors.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: NOT ready biodegradable.
Conclusions:
In the consensus assessment only reliable predictions are to be taken into account. In this case, 2-chloro-4-(1H-pyrazol-5-yl)benzonitrile was predicted as not ready biodegradable by BIOWIN (moderate reliable) and as not ready biodegradable by Toxtree (reliability assessment not applicable). Thus, based on BIOWIN/Toxtree predictions it was concluded that 2-chloro-4-(1H-pyrazol-5-yl)benzonitrile can be moderately reliably predicted as NOT ready biodegradable.