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Biodegradation in water

The predicted data for the test compound(5Or8)-aminonaphthalene-2-sulphonic acid(CAS No. 51548-48-2) and the study for its read across substance were reviewed for the biodegradation end point which are summarized as below:

Estimation Programs Interface Suite (EPI suite, 2016) was run to predict the biodegradation potential of the test compound (5Or8)-aminonaphthalene-2-sulphonic acid (CAS no. 51548 -48 -2). The screening tests ready biodegradability of the test substance was calculated using the software BIOWIN v4.10. The results indicate that (5Or8)-aminonaphthalene-2-sulphonic acid is not expected to be readily biodegradablein nature.

Biodegradation study was conducted (GREIM H, 1994) for 30 days for evaluating the percentage biodegradability of testsubstance

1,3-Naphthalenedisulfonic acid, 6-amino-. No degradation of test substance was determined by BOD in 30 days. Thus, the substance 1,3-Naphthalenedisulfonic acid, 6-amino- is not expected to be readily biodegradable in water.

A batch test in an open system was conducted (P. Pitter, 1976) for evaluating the biodegradability of1-Naphthylamine-6-sulphonic acid. The compound was the sole source of organic carbon for the microbes of the inoculum. Degradation was studied by determining COD (organic carbon). The pH of the biological medium was 7.2. Initial concentration; 125 - 200mg/l COD. Inoculum; Activated sludge, adapted for 20 days, fed by glucose and peptone with simultaneous addition of the substance tested in the concentration up to 125 mg/l. The sludge age was 5 days. Concentration of the inoculum; 100mg/l. Average temperature during the experiment; 20°C. Under the test conditions the compound was found to be biologically hard to decompose(non-biodegradable).

Biodegradation study was conducted (J-CHECK, 2016) for 28 days for evaluating the percentage biodegradability of test substance 2-Amino-1,5-naphthalenedisulfonic acid. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test substance was found to be 1% by BOD, 0% by HPLC and 5% by TOC removal in 28 days. Thus, the substance 2-Amino-1,5-naphthalenedisulfonic acidis not expected to be readily biodegradable in water.

 

Biodegradation study was conducted (J-CHECK, 2016) for 14 days for evaluating the percentage biodegradability of test substanceSodium naphthionate. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test substance was determined to be 0% by BOD, O2 consumption, UV-Vis and Test mat. analysis and < 0%by TOC removal in 14 days. Thus, the substanceSodium naphthionateis not expected to be readily biodegradable in water.

 

On the basis of above results for target and read across substance, it can be concluded that the test substance(5Or8)-aminonaphthalene-2-sulphonic acidcan be expected to be not readily biodegradable in nature.

 

Biodegradation in water and sediment

Estimation Programs Interface (EPI) Suite (2016) prediction model was run to predict the half-life in water and sediment for the test compound (5Or8)-aminonaphthalene-2-sulphonic acid(CAS No. 51548 -48 -2). Half-life of (5Or8)-aminonaphthalene-2-sulphonic acidin water is estimated to be 37.5 days (900 hrs) while in sediment it is 337.5 days (8100 hrs). Based on these half-life value of (5Or8)-aminonaphthalene-2-sulphonic acid, it is concluded that the chemical is not persistent in water while it is persistent in sediment.

Biodegradation in soil

Based on EPI prediction Level III Fugacity Model (EPI suite, 2016), the estimated half-life period of (5Or8)-aminonaphthalene-2-sulphonic acid(CAS No. 51548 -48 -2) in soil was obtained to be 75 days (1800 hrs). Based on this half-life value of (5Or8)-aminonaphthalene-2-sulphonic acid, it isconcluded that the chemical is not persistent in the soil environment.