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Description of key information

The Henry's Law Constant (HLC) of 1,2-dichloro-1-[difluoro(trifluoromethoxy)methoxy]-1,2,2-trifluoroethane is calculated to be 5061050 Pa m3/mol (20°C).

The values indicates that 1,2-dichloro-1-[difluoro(trifluoromethoxy)methoxy]-1,2,2-trifluoroethane has a very high tendency to distribute from water to the gas phase.

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
5 061 050
at the temperature of:
20 °C

Additional information

The Henry's Law Constant (HLC) of 1,2-dichloro-1-[difluoro(trifluoromethoxy)methoxy]-1,2,2-trifluoroethane is calculated according to the following equation:

Henry's Law Constant (HLC) = (VP x MOLW) / WS

(Reference: Guidance on Information Requirements and Chemical Safety Assessment_ Chapter R.16: Environmental Exposure Estimation_ Version 2.1_Equation R.16-4)

where:

VP = Vapour pressure (Pa) = 14000 Pa (at 20°C)

MOLW = Molecular Weight (g/mol) = 302.94 g/mol

WS = Water solubility (mg/L) = 0.838 mg/L (at 20°C)

As reported in Guidance on Information Requirements and Chemical Safety Assessment_Chapter R.7a, substances with HLC values around 100 Pa·m3/mol, will have a rapid volatilisationfrom water. Basing on the calculated Henry’s Law constant value, volatilization of 1,2-dichloro-1-[difluoro(trifluoromethoxy)methoxy]-1,2,2-trifluoroethane from water is expected to be extremely rapid.