Potassium hydrogen phthalate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

05-06-2017 – 09-06-2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental test result performed using standard test guidelines

Qualifier:

according to guideline

Guideline:

other: Shake Flask Method

Principles of method if other than guideline:

The water solubility determination of test substance Potassium hydrogen phthalate (CAS No. 877-24-7) was done as per the shake flask method.

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

- Name of test material (as cited in study report): Hydrogen potassium phthalate
- Molecular formula : C8H5O4K
- Molecular weight : 204.221 g/mol
- Smiles notation : c1(c(cccc1)C(=O)[O-])C(O)=O.[K+]
- InChl : 1S/C8H6O4.K/c9-7(10)5-3-1-2-4-6(5)8(11)12;/h1-4H,(H,9,10)(H,11,12);/q;+1/p-1
- Substance type:Organic
- Physical state:Solid

Key result

Water solubility:

82 658.7 mg/L

Temp.:

29 °C

Remarks on result:

other: no other details available

Details on results:

The water solubility determination of test substance Potassium hydrogen phthalate was done as per the shake flask method. The solubility was found to be 82658.7 mg/L at 30°C.

Sample stirring	Concentration obtained on	Dilution factor	Solubility value obtained
	the basis of standard curve		(mg/L)
24 hour	-	-	-
48 hour	39.8564	2000	79712.8
72 hour	42.8023	2000	85604.6

Conclusions:

Interpretation of results (migrated information): very soluble (> 10000 mg/L)

The water solubility determination of test substance Hydrogen potassium phthalate was done as per the shake flask method. The solubility was observed to be 82658.7 mg/L at 29°C. Thus the chemical is considered to be very soluble.

Executive summary:

The water solubility determination of test substance Hydrogen potassium phthalate was done as per the shake flask method. The solubility was observed to be 82658.7 mg/L at 29°C. Thus this value suggest that the chemical is considered to be very soluble.

Description of key information

The water solubility determination of test substance Hydrogen potassium phthalate was done as per the shake flask method. The solubility was observed to be 82658.7 mg/L at 30°C. Thus this value suggest that the chemical is considered to be very soluble.

Key value for chemical safety assessment

Water solubility:

82 658.7 mg/L

Additional information

Summarized result for the water solubility determination of test substance Hydrogen potassium phthalate.

In the first study the water solubility determination of test substance Hydrogen potassium phthalate was done as per the shake flask method. The solubility was observed to be 82658.7 mg/L at 30°C. Thus this value suggest that the chemical is considered to be very soluble.

Similarly a study was conducted to determine the water solubility of hydrogen potassium phthtlate at various temperatures. The water solubility of hydrogen potassium phthalate was determined to be 83 g/l at 20 deg C and 330 g/l at 100 deg C. These values suggests that hydrogen potassium phthalate is highly soluble in water.

Data from authoritative and estimated databases suggests that the water solubility of hydrogen potassium phthalate was determined to be 83300 mg/l. This value suggests that hydrogen potassium phthalate is highly soluble in water.

Thus based on the above studies, chemical consider to be very soluble in water.