Registration Dossier
Registration Dossier
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EC number: 700-181-2 | CAS number: -
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Study period:
- 72 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Summary of study conducted. Not a full report. No discussion of controls provided.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Report date:
- 1990
Materials and methods
- Test type:
- standard acute method
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- Name of test material (as cited in study report): DOB-AA
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- 2 males; 2 females
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- unchanged (no vehicle)
- Duration of exposure:
- 72 hours
- Doses:
- 0.5 cc
- No. of animals per sex per dose:
- Each animal (2 males, 2 females) dosed with 0.5 cc of 100% DOB-AA test material (moistened with saline).
- Control animals:
- not specified
Results and discussion
- Preliminary study:
- No dermal irriation observed
- Mortality:
- Not applicable
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: expert judgment
- Conclusions:
- DOB-AA was non-irritating to the skin. All four animals were free of dermal irritation.
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