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In water, nitrosylsulfuric acid (HNO5S) decomposes at ambient temperature into sulfuric acid (H2O4S) and nitrous acid (HNO2). Nitrous acid is also not stable in water at ambient temperature and decomposes into nitric oxide (NO) and nitrate ion (NO3-). That is the reason why the assessment of the toxicity of nitrosylsulfuric acid is based on the toxicological properties of its breakdown products in water: sulfuric acid and nitrate ions.

Three key studies are available for the aquatic toxicity endpoints: one for the short-term toxicity to fish, one for short-term toxicity to aquatic invertebrates and the other for the algae.


Short-term toxicity to fish:

- LC50 (96h) = 16 - 28 mg/L (No guideline) (reliability: 2e)

Short-term toxicity to aquatic invertebrates:

- EC50 (48h) > 100 mg/L (OECD Guideline 202; EU Method C.2) (reliability 1).

Toxicity to aquatic algae:

- ErC 50 (0-72 h): > 100 mg/L with the correspondingNOEC [r] of 100 mg/L

Based on the results of these information, nitrosylsulfuric acid is considered as harmful (R52) to the aquatic organisms tested in accordance with the Directive 67/548/EC. According to GHS, the substance is not classified.