Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
basic toxicokinetics
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1976 – 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Objective of study:
other: corrosive/ irritation effects... (see attached file)
Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Occupational Medical Assessment
GLP compliance:
no

Test material

Test animals

Species:
human
Sex:
male

Administration / exposure

Route of administration:
inhalation: dust
Vehicle:
unchanged (no vehicle)
Details on exposure:
dermal exposition
Duration and frequency of treatment / exposure:
n.a.
Doses / concentrations
Remarks:
Doses / Concentrations:
n.a.
No. of animals per sex per dose / concentration:
n.a.
Control animals:
no

Results and discussion

Applicant's summary and conclusion

Executive summary:

No indication of specific target-organic toxicity could be determined. This also applies for effects on the respiratory tract and the mucous membranes.