Registration Dossier
Registration Dossier
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EC number: 701-015-1 | CAS number: 2156592-72-0
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
No sediment toxicity study with the target substance is available. Data generated with the category substance LABS Na was considered pitoval to this endpoint.
Three sediment toxicity studies are available for the substance LABS Na.
The first study (Comber et al. 2006) determined the toxicity to sediment dwelling worms. Exposure lasted 28 days, at which time the organisms were observed for survival and biomass. The test substance half-life in aerobic sediment was approximately 20 days. The EC50 was ≥ 105 mg/kg sediment dry weight. The NOEC was 81 mg/kg sediment dry weight.
In the second study (Comber et al. 2006) test organisms of the nematode species Caenorhabditis elegans were tested. Exposure lasted 3 days, at which time the organisms were observed for survival and reproduction. The NOEC for egg production was 100 mg/kg sediment dw, the NOEC for fertility was 200 mg/kg sediment dw and the EC10 for growth was 275 mg/kg sediment dw.
In the final toxicity study (Pittinger et al. 1989; The Procter & Gamble Company 1986; van de Plassche et al 1999) the midge Chironomus ripariu, was exposed to LABS Na for 24 days. The 72 hour LC50 was between 1.0 and 4.7 mg/L, based on survival of newly hatched larvae. In the partial life cycle bioassay in a flow-through sediment/water test system (chronic test), percentages of winged adults emerging after continuous exposure of larvae and pupae to a range of LAS concentrations were determined. Exposure concentrations in sediment, interstitial water and overlying water were monitored by14C liquid scintillation counting. The effect of LAS level in the water column was determined in a total of six chronic toxicity tests. The NOECs from these tests ranged from 2.4 to 3.0 (without sediment), and 3.0 to 6.0 (with sediment). The effect of LAS on Chironomus was also evaluated in an experiment using sediment spiked with LAS. In this test, the NOEC of sediment-spiked LAS was 319 mg/kg sediment (dry weight basis).
Key value for chemical safety assessment
- EC10, LC10 or NOEC for freshwater sediment:
- 81 mg/kg sediment dw
- EC10, LC10 or NOEC for marine water sediment:
- 8.1 mg/kg sediment dw
Additional information
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