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Ecotoxicological information

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Aquatic toxicity studies in invertebrates and plants were performed according to standard guidelines to evaluate the toxicity potential of the structural analogue substance.

Two weight of evidence studies showed that the read-across test item does not have acute toxic effects on Daphnia magna and lead to a 48h EC50 greater than 100 mg/L. A study was performed to assess the effect of the read-across test item on the growth of the freshwater plant Lemna minor. The effect of the read-across test item on the growth of Lemna minor was investigated over a 7 -day period and gave the following results. The average specific growth rate (frond number) EC50 was >100 mg/L. The average specific growth rate (dry weight) EC50 was >100 mg/L. The NOEC was 100 mg/L.

Based on the test data for plants and daphnids (EC50 >100 mg/L) the structural analogue can be classified as not toxic to aquatic organisms. Therefore the target substance should not be classified either.