Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
melting point/freezing point
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Justification for type of information:
REPORTING FORMAT FOR THE ANALOGUE APPROACH

1. HYPOTHESIS FOR THE ANALOGUE APPROACH
This read-across is based on the hypothesis that the source and the target substance have very similar physicochemical and (eco)toxicological properties because their chemical structures are nearly identical. An analogue approach has thus been employed. The target substance is the meta-isomer of the dye Reactive Blue 049, where the sulphonate group is bound at the meta-position of the aminobenzene moiety. The source chemical is the reaction mass of both the meta-isomer and the para-isomer of Reactive Blue 049.
The presence of sulphonate groups make both dyes highly water soluble and therefore less critical for human health and environmental issues. Based on their chemical similarity, similar properties are expected in both humans and the environment.

2. SOURCE AND TARGET CHEMICAL(S)
Source: Reactive Blue 49 meta/para (CAS# 72214-18-7 / EC# 276-481-8)
Target: Reactive Blue 49 meta (CAS# 72927-99-2 / EC# 277-040-2)

3. ANALOGUE APPROACH JUSTIFICATION
see attachment under 4.2 Melting point / freezing point
Reason / purpose for cross-reference:
read-across source
Melting / freezing pt.:
> 330 °C
Atm. press.:
ca. 1 013 hPa
Decomposition:
yes
Decomp. temp.:
330 °C
Remarks on result:
not determinable
Remarks:
No melting point up to 330 °C when decomposition starts
Conclusions:
No melting point detected (until the decomposition temperature approx. 330 °C).
Executive summary:

The melting point of the test item was determined according to OECD Guideline 102.The test results showed no melting point detected until the decomposition temperature approx. 330 °C.

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Principles of method if other than guideline:
None
GLP compliance:
no
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
Name of test material: FAT 41001/H TE
Melting / freezing pt.:
> 330 °C
Atm. press.:
ca. 1 013 hPa
Decomposition:
yes
Decomp. temp.:
ca. 330 °C
Remarks on result:
not determinable
Remarks:
No melting point up to 330 °C when decomposition starts

None

Conclusions:
No melting point detected (until decomposition temperature approx. 330 °C).



Executive summary:

The melting point of the test item was determined according to OECD Guideline 102.The test results showed no melting point detected until the decomposition temperature approx. 330 °C.

Description of key information

No melting point detected (until the decomposition temperature approx. 330 °C). 

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
330 °C

Additional information

The melting point of the source substance was determined according to OECD Guideline 102. The test results showed no melting point detected until the decomposition temperature of approx. 330 °C. The structurally related target substance will not melt either, and will decompose before melting, like many other reactive dyes.