Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic / sediment

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical (authoritative database, 2017). The bioaccumulation factor (BCF) value was calculated using a logKow of 3.85 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 161 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is considered to be non-accumulative in aquatic organisms.

Additional information

Bioaccumulation: aquatic / sediment

Various experimental key and supporting studies of the test chemical were reviewed for the bioaccumulation end point which are summarized as below:

 

In an experimental key study from authoritative database (2017), bioaccumulation experiment in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a logKow of 3.85 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 161 dimensionless.

 

Another bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical (from handbook, 2008). The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 501 dimensionless.

 

For the test chemical, the bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a measured logKow of 4.0 and an equation (logBCF (fish) = 0.85*logKow – 0.70). The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 501 dimensionless.

 

On the basis of above results for test chemical(from authoritative database and handbook, 2017), it can be concluded that the BCF value of test substancewas evaluated to be upto 501,which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.