Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: peer reviewed literature information
Adequacy of study:
other information

Data source

Reference
Reference Type:
review article or handbook
Title:
SIDS Initial Assessment Report Isobutanol 78-83-1
Author:
United States of America, U.S. Environmental Protection Agency
Year:
2001
Bibliographic source:
OECD

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EPA OTS 798.1175 (Acute Oral Toxicity)

Test material

Reference
Name:
Unnamed
Test material form:
liquid

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
> 2 830 mg/kg bw
Sex:
female
Dose descriptor:
LD50
Effect level:
3 350 mg/kg bw

Applicant's summary and conclusion