Registration Dossier

Administrative data

First-aid measures

- 4.1 Description of first aid measures
- General information
Instantly remove any clothing soiled by the product.
Remove breathing apparatus only after soiled clothing has been completely removed.
In case of irregular breathing or respiratory arrest provide artificial respiration.
- After inhalation
Supply fresh air or oxygen; call for doctor.
In case of unconsciousness bring patient into stable side position for transport.
- After skin contact Instantly wash with water and soap and rinse thoroughly.
- After eye contact Rinse opened eye for several minutes (10 - 15) under running water. Then consult doctor.
- After swallowing Do not induce vomiting; instantly call for medical help.
- 4.2 Most important symptoms and effects, both acute and delayed
Dyspnoea, wheezing, respiratory depression
Dazed, lightheadedness
Unconsciousness
Confusion
Tachycardia
Dizziness
Cyanosis
Headache
Gastric or intestinal trouble
Nausea, vomiting
Salviation
Narcosis, coma
- Information for doctor Pharmacological group: Neuroleptic drug
- Danger
Danger of system failure.
Danger of pneumonia.
Danger of apnea.
Danger of Hypotonie.
- 4.3 Indication of any immediate medical attention and special treatment needed
No specific antidote available. Treat symptomatically and supportively.
Monitoring or correction of vital functions.
Monitor circulation, possible shock treatment.
In cases of cyanosis, administer vitamin C, oxygen, protect from sunlight.

Fire-fighting measures

- 5.1 Extinguishing media
- Suitable extinguishing agents
CO2, extinguishing powder or water jet. Fight larger fires with water jet or alcohol-resistant foam.
- For safety reasons unsuitable extinguishing agents Do not use a heavy water stream.
- 5.2 Special hazards arising from the substance or mixture
Can form explosive gas-air mixtures.
Formation of toxic gases is possible during heating or in case of fire.
Can be released in case of fire
Nitrogen oxides (NOx)
Hydrogen chloride (HCl)
Hydrogen fluoride (HF)
- 5.3 Advice for firefighters
- Protective equipment:
Wear self-contained breathing apparatus.
Do not inhale explosion gases or combustion gases.
Wear full protective suit.
- Additional information
Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.
Combustible.

Accidental release measures

- 6.1 Personal precautions, protective equipment and emergency procedures
Ensure adequate ventilation
Wear protective equipment (described in section 8). Keep unprotected persons away.
Avoid causing dust.
Do not inhale dust.
Avoid contact with substance.
Do not inhale fumes/aerosol.
- 6.2 Environmental precautions: Do not allow product to reach sewage system or water bodies.
- 6.3 Methods and material for containment and cleaning up:
Dispose of contaminated material as waste according to item 13.
Collect mechanically.
Ensure adequate ventilation.

Handling and storage

- 7.1 Precautions for safe handling
Thorough dedusting.
Ensure good ventilation/exhaustion at the workplace.
Open and handle container with care.
Prevent formation of dust.
Prevent formation of aerosols.
- Information about protection against explosions and fires:
Keep ignition sources away - Do not smoke.
Protect against electrostatic charges.
Keep breathing equipment ready.
- 7.2 Conditions for safe storage, including any incompatibilities
- Storage
- Requirements to be met by storerooms and containers: Store in cool location.
- Information about storage in one common storage facility: Not required.
- Further information about storage conditions:
Keep container tightly closed.
Store in cool, dry conditions in well sealed containers.
Store in a locked cabinet or with access restricted to technical experts or their assistants.
- 7.3 Specific end use(s) No further relevant information available.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

- Additional information about design of technical systems: No further data; see item 7.
- 8.1 Control parameters
- Components with limit values that require monitoring at the workplace: Not required.
- DNELs (Derived no-effect level) No information available
- PNECs (predicted no effect concentration) No information available
- Additional information:
The lists that were valid during the compilation were used as basis.
OEL (Pfizer): 1 ug/m³ (-)
Haloperidol
- 8.2 Exposure controls
- Personal protective equipment
- General protective and hygienic measures
The usual precautionary measures should be adhered to general rules for handling chemicals.
Keep away from foodstuffs, beverages and food.
Take off immediately all contaminated clothing
Wash hands during breaks and at the end of the work.
Store protective clothing separately.
Avoid contact with the eyes and skin.
Do not inhale dust
- Breathing equipment:
In case of brief exposure or low pollution use breathing filter apparatus. In case of intensive or longer
exposure use breathing apparatus that is independent of circulating air.
- Recommended filter device for short term use:Combination filter ABEK (DIN 3181), Filter AX DIN EN 371
- Protection of hands:Protective gloves (EN 374).
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/
the chemical mixture.
- Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality
and varies from manufacturer to manufacturer.
- Penetration time of glove material
The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be
observed.
- Eye protection:Tightly sealed safety glasses.
- Body protection: Protective work clothing.

Stability and reactivity

- 10.1 Reactivity No further relevant information available.
- 10.2 Chemical stability
- Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
- 10.3 Possibility of hazardous reactions Forms explosive gas mixture with air
- 10.4 Conditions to avoid No further relevant information available.
- 10.5 Incompatible materials: Strong oxidizing materials
- 10.6 Hazardous decomposition products:
Hydrogen chloride (HCl) / hydrochloric acid
Hydrogen fluoride
Nitrogen oxides (NOx)

Disposal considerations

- 13.1 Waste treatment methods
- Recommendation
After prior treatment product has to be disposed of in an incinerator for hazardous waste under adherence to
the regulations pertaining to the disposal of particularly hazardous waste.
- Uncleaned packagings:
- Recommendation:
Disposal must be made according to official regulations.
Packaging must be disposed of in compliance with country-specific regulations or must be passed to a
packaging return system.