Registration Dossier

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
In silico
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Justification for type of information:
QSAR prediction

Data source

Reference
Reference Type:
other: Predicted data
Title:
Unnamed
Year:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: REACH guidance on QSARs R.6, May/July2008
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Test material form:
solid: crystalline

Results and discussion

In vivo

Results
Irritation parameter:
other: Primary Irritation Index
Score:
2.99
Remarks on result:
other: Database: Skin irritation

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritant) based on GHS criteria
Conclusions:
According to (Q)SAR modell: QSAR Toolbox, the predicted value indicated that (-)-hydroxymethyl-tetrahydropiridine-L-dibenzoyl-tartarate is irritating to skin. The result meets the requirement of Hazard Category 2.