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Ecotoxicological information

Short-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
September 18, 1975
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
abstract
Qualifier:
according to guideline
Guideline:
other: Internal method 11
Deviations:
not specified
Principles of method if other than guideline:
At Ciba Geigy AG acute fish toxicity testing was performed according to published methods, which were adapted and standardized for the specific needs of the company, well before Test Guidelines for these methods were established by the OECD beginning 1981.
GLP compliance:
no
Test organisms (species):
not specified
Details on test organisms:
- Test organisms: Trouts
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
pH:
7.8 - 8.1
Nominal and measured concentrations:
NOMINAL: 100, 200, 1000 mg/l
Details on test conditions:
No. of organisms tested 8
Key result
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
ca. 450 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC0
Effect conc.:
ca. 200 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC100
Effect conc.:
ca. 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Conclusions:
The substance shows a LC50(48h) = 450 mg/l
Executive summary:

The substance has been tested with acute fish toxicity according to the CIBA GEIGY internal method 11. 8 Salmo gairdneri are tested at concentration of 100, 200 and 1000 mg/l. The substance shows a LC50(48h) = 450 mg/l

Description of key information

LC50(48h) = 450 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
450 mg/L

Additional information

In order toevaluate the toxicity to fish, the substance was tested according to a Ciba-Geigy internal method (n.11). Eight fish were exposed to the target substance at the following concentrations: 100, 200 and 1000 mg/l. The mortality of the tested organisms was observed after 24 and 48 hours of exposure. Based on the mortality observed the LC50 was calculated to be 450 mg/l