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Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
The justification of the read across category approach is included in IU section 13.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzenesulfonic acid, methyl-, C20-24 (even numbered) sec-alkyl derivs.
EC Number:
939-185-6
Molecular formula:
C8H11(CH2)nSO3 n=19-23
IUPAC Name:
Benzenesulfonic acid, methyl-, C20-24 (even numbered) sec-alkyl derivs.
Test material form:
liquid: viscous
Details on test material:
Appearance: viscous opaque suspension

Results and discussion

Test results
Sex:
male/female
Genotoxicity:
negative
Toxicity:
no effects
Vehicle controls validity:
valid
Negative controls validity:
valid
Positive controls validity:
valid

Applicant's summary and conclusion

Conclusions:
No genetic toxicity study with thetarget substance is available. Data generated with the category substance LABS Na is considered pivotal. Therefore, the target substance is considered to not be mutagenic.

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