(1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-

GHS

General Information

Name:

Pipamperone - CLP classification

Implementation:

EU

Remarks:

This substance is currently listed on the substances list published by ECHA of those whose met REACH Annex III criteria:

# Suspected carcinogen: The Toolbox profiler Carcinogenicity (genotox and nongenotox) alerts by ISS gives an alert for carcinogenicity

# Suspected hazardous to the aquatic environment:

Fish toxicity classification (SarPy/IRFMN) model in VEGA (Q)SAR platform predicts that the chemical is Toxic-3 (between 10 and 100 mg/l) (good reliability);

The Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 46.9 mg/L;

The Danish QSAR database contains information indicating that the substance has a 48h EC50 to Daphnia of 5.78 mg/L;

The Danish QSAR database contains information indicating that the substance has a 96h EC50 to green algae of 2.35 mg/L

# Suspected persistent in the environment: The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable

The Annex III inventory is an advisory list, there are not detailed information about the used model and the predictions do not follow OECD principles.

The above data can only be used as screening information; they are not to be considered relevant for the classification and labelling, but only in support to the available data.

Related composition

Related composition:

Composition

Classification

Physical hazards

Explosives

Reason for no classification:

data lacking

Flammable gases and chemically unstable gases

Reason for no classification:

data conclusive but not sufficient for classification

Aerosols

Reason for no classification:

data conclusive but not sufficient for classification

Reason for no classification:

hazard class not assessed

Oxidising gases

Reason for no classification:

data conclusive but not sufficient for classification

Gases under pressure

Reason for no classification:

data conclusive but not sufficient for classification

Flammable liquids

Reason for no classification:

data conclusive but not sufficient for classification

Flammable solids

Reason for no classification:

data lacking

Self-reactive substances and mixtures

Reason for no classification:

data lacking

Pyrophoric liquids

Reason for no classification:

data conclusive but not sufficient for classification

Pyrophoric solids

Reason for no classification:

data lacking

Self-heating substances and mixtures

Reason for no classification:

data lacking

Substances and mixtures which in contact with water emit flammable gases

Reason for no classification:

data lacking

Oxidising liquids

Reason for no classification:

data conclusive but not sufficient for classification

Oxidising solids

Reason for no classification:

data lacking

Organic peroxides

Reason for no classification:

data conclusive but not sufficient for classification

Corrosive to metals

Reason for no classification:

data lacking

Desensitized explosives

Reason for no classification:

data lacking

Health hazards

Acute toxicity - oral

Hazard category:

Acute Tox. 3

Hazard statement:

H301: Toxic if swallowed.

Acute toxicity - dermal

Reason for no classification:

data lacking

Acute toxicity - inhalation

Reason for no classification:

data lacking

Skin corrosion / irritation

Reason for no classification:

data conclusive but not sufficient for classification

Serious eye damage / eye irritation

Reason for no classification:

data conclusive but not sufficient for classification

Respiratory sensitisation

Reason for no classification:

data lacking

Skin sensitisation

Reason for no classification:

data conclusive but not sufficient for classification

Aspiration hazard

Reason for no classification:

data lacking

Reproductive toxicity

Reason for no classification:

data lacking

Effects on or via lactation

Reason for no classification:

data lacking

Germ cell mutagenicity

Reason for no classification:

data conclusive but not sufficient for classification

Carcinogenicity

Reason for no classification:

data conclusive but not sufficient for classification

1. Specific target organ toxicity - single (STOT-SE)

Reason for no classification:

data lacking

1. Specific target organ toxicity - repeated (STOT-RE)

Reason for no classification:

data lacking

Environmental hazards

Hazardous to the aquatic environment (acute / short-term)

Reason for no classification:

data conclusive but not sufficient for classification

Hazardous to the aquatic environment (long-term)

Hazard category:

Aquatic Chronic 2

Hazard statement:

H411: Toxic to aquatic life with long lasting effects.

Hazardous to the ozone layer

Reason for no classification:

data lacking

Labelling

Signal word:

Danger

Hazard pictogram

GHS06: skull and crossbones

GHS09: environment

Hazard statements

H301: Toxic if swallowed.

H411: Toxic to aquatic life with long lasting effects.