Registration Dossier

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary resource Phenol is a major component of the reaction mass, so that phenol hazard data are applied in the hazard assessment.

Data source

Reference
Reference Type:
publication
Title:
Summary review of the health effects association with phenol.
Author:
Bruce RM, Santodonato J and Neal MW .
Year:
1987
Bibliographic source:
Toxicol. Ind. Health 3, 535-568

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
acute toxicity: oral

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenol
EC Number:
203-632-7
EC Name:
Phenol
Cas Number:
108-95-2
Molecular formula:
C6H6O
IUPAC Name:
phenol

Method

Route of exposure:
oral

Results and discussion

Results of examinations:
Oral toxicity of phenol in humans leading to the death of the victim is reported for doses as low as 140-290 mg/kg body weight.

Applicant's summary and conclusion