Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Direct observations: clinical cases, poisoning incidents and other

Currently viewing:

Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary resource Phenol is a major component of the reaction mass, so that phenol hazard data are applied in the hazard assessment.

Data source

Reference
Reference Type:
publication
Title:
Summary review of the health effects association with phenol.
Author:
Bruce RM, Santodonato J and Neal MW .
Year:
1987
Bibliographic source:
Toxicol. Ind. Health 3, 535-568

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
acute toxicity: oral

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenol
EC Number:
203-632-7
EC Name:
Phenol
Cas Number:
108-95-2
Molecular formula:
C6H6O
IUPAC Name:
phenol

Method

Route of exposure:
oral

Results and discussion

Results of examinations:
Oral toxicity of phenol in humans leading to the death of the victim is reported for doses as low as 140-290 mg/kg body weight.

Applicant's summary and conclusion