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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

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Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data published in peer-reviewed literature.
Principles of method if other than guideline:
In the peer-reviewed handbook only the dissociation constant is reproted but not the test guideline.
GLP compliance:
not specified
Dissociating properties:
yes
No.:
#1
pKa:
9.89
Temp.:
20 °C
Conclusions:
The dissociation constant of phenol is 9.89 at 20 °C.
Executive summary:

In the peer-reviewed handbook the dissociation constant of phenol is reported to be 9.89 at 20 °C.

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Lack of experimental details
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Dissociating properties:
yes
No.:
#1
pKa:
>= 11.3
Remarks on result:
other: temperature not specified
Executive summary:

The acid-base constant of Bisphenol A is 11.3.

Description of key information

The acid-base constant of Bisphenol A is 11.3. The dissociation constant (pKa) of phenol is reported to be 9.89 at 20 °C.

Key value for chemical safety assessment

Additional information

In the peer-reviewed handbook the dissociation constant of phenol is reported to be 9.89 at 20 °C.

The acid-base constant of Bisphenol A is 11.3.