2-[alkyl(4-nitrosoaryl)amino]alkyl [3-(trialkoxysilyl)propyl]carbamate

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Guideline study and GLP

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Report date:

2015

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 111 (Hydrolysis as a Function of pH)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

[CS]000000419807[/CS]

IUPAC Name:

[CS]000000419807[/CS]

Constituent 2

Reference substance name:

[SPEC][/SPEC][SYN][/SYN]

IUPAC Name:

[SPEC][/SPEC][SYN][/SYN]

Results and discussion

Dissipation DT50 of parent compound

Dissipation DT50 of parent compound 1

pH:

4

Temp.:

20 °C

Remarks on result:

other: not determined: At pH 4 an immediate hydrolysis takes place.

Dissipation DT50 of parent compound 2

pH:

7

Temp.:

20 °C

Hydrolysis rate constant:

0.011 h-1

DT50:

61.9 h

Dissipation DT50 of parent compound 3

pH:

9

Temp.:

20 °C

Hydrolysis rate constant:

0.111 h-1

DT50:

6.2 h

Applicant's summary and conclusion

Conclusions:

The test item is hydrolytically unstable at pH4, pH7 and pH9