Registration Dossier

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Between 4 March 2009 and 29 May 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Recently conducted GLP compliant study using the most recent test methods

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report Date:
2009

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): JKY-214
- Physical state: white solid
- Analytical purity: No information
- Lot/batch No.: Y002E
- Expiration date of the lot/batch: No information
- Stability under test conditions: No information. Assumed stable due to no data to the contrary
- Storage condition of test material: room temperature in the dark
- Other:

Results and discussion

Boiling point
Boiling pt.:
667 K
Decomposition:
yes
Remarks:
demonstrated by black residue in the crucible
Remarks on result:
other: Similar thermographic profiles were obtained in air and nitrogen atmospheres indicating that the observed decomposition is probably thermal and not oxidative.

Any other information on results incl. tables

The temperature at which thermal events occur over an increasing temperature between 0 and 440oC increasing steadily over a 25 minute period. The results are provided below

Thermographic Data - Determination 1

 

Thermal Event

  Interpretation    Temperature 
 Extrapolated onset of endotherm Onset of boiling with decomposition   394oC  667K

Thermographic Data - Dertermination 2

 

Thermal Event

    Interpretation       Temperature 
  Extrapolated onset of endotherm   Onset of boiling with decomposition  394oC 667K 

Applicant's summary and conclusion

Conclusions:
The test material has been determined to boil with decomposition from 667 ± 0.5K at 99.98 kPa
Executive summary:

The boiling temperature has been assessed using Differential Scanning Calorimetry (DSC) according to EU method A2 in compliance with GLP. Using a calibrated Differential Scanning Calorimeter, the temperature at which an endotherm event equivalent to the boiling temperature recorded in duplicate. Taking an average of the recorded exothermic events, the boiling temperature was determined to onset at 667±0.5K with decomposition, as evidenced by black residue in the crucible after each determination.